Researchers at the University of St. Louis School of Medicine in the United States, in a study reviewing the medical history of 1.3 million adults over a five-year period, found that kidney dysfunction could cause diabetes, and furthermore, a waste product called ‘ Urea is associated with a relationship between the two diseases.
Urea is obtained from the protein breakdown of food. Kidneys usually remve urea from the blood, but poor renal function can lead to an increase in urea levels in the blood.
About 9 percent of the 1.3 million adults examined in this study showed high levels of urea in their blood, indicating a decrease in renal function.
The study, recently published in the Kidney International online magazine, found that people with high levels of urea had a 23% higher chance of developing diabetes than those with normal blood urea.
According to researchers, the risk difference between high and low urea levels is 688 cases of diabetes per 100,000 per year. This means that every year, every 100,000 people have 688 more cases of diabetes in people with higher levels of urea.
Researchers have long been aware that diabetes is a major risk factor for kidney disease, but now they have received better information that kidney disease also increases the risk of diabetes by increasing urea levels. .
They noted that when urea accumulates in the blood due to impaired renal function,
The body’s resistance to insulin increases and often leads to weakening of insulin secretion.
The findings of this study on the role of urea can help to strengthen the treatment and possibly prevent diabetes. Urea levels can be reduced in a variety of ways, including taking medication and diet.